KPV is a three-amino-acid anti-inflammatory peptide fragment of alpha-MSH, studied for gut and skin inflammation. It is compounded and not FDA-approved as a finished drug. Ivologist prescribes it as capsules or within the KLOW combination vial after a medical telehealth consultation.
KPV Peptide
A physician-supervised KPV protocol for gut and skin inflammation. KPV is a three-amino-acid fragment of alpha-MSH studied for targeted anti-inflammatory action, available as capsules or within a combination vial. Programs include an online provider consultation, medication, supplies, and ongoing clinician guidance. Eligibility is determined by a licensed healthcare provider.
You save $99
- Clinician consultation
- Peptide medication
- Free shipping
- May require labs
One-time payment, not a subscription. Up to 3 cycles per year. A cycle is the program length; your provider decides whether treatment is right for you and sets your dose, schedule and duration. We do not offer clinical trials. Individual results may vary.
- 43,000+Patients served
4.8Google rating- US-licensed503A Pharmacies
Studied in lab and animal research for gut-lining inflammation, including IBS and colitis pictures. No completed human trial as a single agent.
Researched, mostly in the lab, for inflammatory skin, flares and redness.
An oral option — capsules, nothing to inject.
Integrates with broader care as the anti-inflammatory arm of KLOW and Quell.
Clinician-guided treatment, prescribed after a provider evaluation.
All treatment plans require medical evaluation and approval. Individual results may vary.
Take control of your health in 6 simple, affordable steps
Personalized Intake
Tell us about your health, goals, and history through a secure intake questionnaire.
Clinician Review
A licensed clinician reviews your information and determines what's right for you.
Diagnostic Lab Testing
Baseline lab work checks your health markers before any peptide is prescribed.
Clinical Evaluation
A provider reviews your labs with you in a live video visit and confirms your suitability for peptide therapy.
Medication Delivered
Your prescribed medication is prepared by a partner pharmacy and shipped to your home.
Ongoing Support
Your progress is monitored with follow-ups and adjustments as needed.
Built around 12-week cycles
Peptide programs are sold in 12-week cycles (about 3 months). You can buy one cycle or a bundle of up to 3 cycles up front, with a maximum of 3 cycles per year.
Labs and a provider consultation are required.
Every peptide program starts with lab work and a live consultation with a licensed provider before anything is prescribed.
- Lab panel includedOne cycle at a time
- Bundle of 2 · save 7.5%
- Bundle of 3 · save 12.5%
- Clinician consultation & follow-up access
- All peptide medication for the cycle
- Shipping to your door
- Injection supplies & dosing guide
Peptide therapy
Not sure which peptide program is right for you?
Talk it through first in a free 15-minute provider consultation. A U.S.-licensed provider will go over your goals and health history, explain how the programs work, and help you decide whether one is right for you before you commit to a cycle. There is no obligation to start treatment.
Book a Free Provider Consultation
Understanding KPV and inflammation
How a melanocortin fragment quiets an overactive local immune response. Learn how clinician-guided KPV may support gut and skin inflammation without broad immune suppression.
Understanding KPV & Inflammation
Learn about KPV, how it works inside gut and skin cells, and how clinician-guided therapy may fit your care plan.
The Physiology
Proposed Melanocortin Anti-Inflammatory Pathway
α-MSH fragment (KPV) → PepT1 transport → NF-κB blocked → less inflammatory signaling
KPV is the three-amino-acid tail (lysine–proline–valine) of alpha-MSH, one of the body's own anti-inflammatory hormones. It carries the anti-inflammatory activity without the pigmentation effects of the parent molecule.
In laboratory studies, inside gut and skin cells it blocks NF-κB, the switch that drives the inflammatory cascade — a targeted action rather than broad immune suppression. The transporter that carries it into the gut lining, PepT1, becomes more active where the gut is inflamed, which is why researchers expect KPV to concentrate where the problem is.
That mechanism is well described in laboratory work. KPV has not yet been properly studied in people as a single agent, and your provider will say so before you consent.
Symptoms
Symptoms & Signals
KPV is considered when patterns like these are present:
Experiencing multiple patterns may warrant clinician evaluation.
Who Is It For?
Who May Benefit from KPV?
KPV may be considered for adults who are:
Clinical evaluation is required. Your eligibility will be determined by a licensed provider.
Capsules vs Injection
KPV Capsules vs Injectable KPV
Two routes to the same peptide — your provider chooses.
Oral capsules
500 mcg capsules taken daily; nothing to inject.
- Designed to reach the gut lining (PepT1 transport, lab studies)
- The needle-free option — the KPV in the Quell program
- Stored at room temperature
Injectable (KLOW combination vial)
KPV combined with BPC-157, TB-500 and GHK-Cu in one vial.
- •One injection routine for the KLOW blend; the blend itself has not been studied
- •Chosen when there is a musculoskeletal or skin-repair component
Route is a provider decision. A patient on both KLOW and Quell takes KPV by two routes — deliberately, never by accident.
Protocol
Protocol Philosophy
KPV is studied as an anti-inflammatory signal, so any response tends to build gradually over a cycle rather than overnight.
An example, not your plan. On this page KPV comes as daily capsules or inside the KLOW combination vial; your provider chooses the route. The 12-week cycle you choose is the program: clinician consultation, peptide medication and free shipping; labs may be required. It is not a dosing schedule; your provider decides your dose, how often and for how long.
Early Phase (Weeks 1–2)
Protocol begins and your baseline is recorded.
Adaptation Phase (Weeks 3–4)
Your body adjusts; no dramatic change is expected yet.
Progression Phase (Weeks 4–6)
Some people report easing symptoms. This is not guaranteed.
Assessment (Weeks 8–12)
Reviewed together against what you described at the start.
Responses vary by individual.
Research Findings and Limits
Research Findings and Limits
What KPV has been studied for, and the kind of study behind each:
Limits of the research. KPV's evidence is mainly laboratory and animal work, with no completed human trial as a single agent. No outcome is guaranteed.
Individual responses vary.
Designed for Safety.Guided by Clinicians.
- Targeted, not immunosuppressive — in lab studies KPV calms inflammation inside gut and skin cells rather than suppressing the immune system broadly
- Gradual, not instant — some people report easing around weeks 4–6, though this is not guaranteed, and your provider reviews at 8–12 weeks
- One peptide, one plan — your provider chooses the route and checks you aren't already taking KPV inside KLOW or Quell
KPV is excluded in pregnancy and breastfeeding, and your full medication list and any other programs are reviewed before it is prescribed
Our patients trust us because we combine real medicine with real care.
DeRonica Lamb
Patient
I was met with professionalism by Michael. He was very knowledgeable and an expert with starting the IV. Only took one attempt which I was grateful for. I've experienced medical st...
Cheryl Taylor
Patient
Was in Dallas @ conference, 1st time trying an IV with magnesium support, was comfortable and easy to do, afterwards felt a difference in my sleep where I had more restful sleep. I...
Keith Akada
Patient
Have always heard from friends the benefits of having an IV. Now I am a believer. First timer and the experience and results were great. For sure was a refresher I could tell my bo...
Mending Vines Foundation
Patient
I've been feeling fatigued and foggy. Madeline was on time, efficient, great to talk with. I highly recommend!!! Next treatment in 2 weeks!
joann pena
Patient
I absolutely love this company! I use the bags when I am not feeling well and they always make me feel better so quickly! It is so convenient that they come directly to you for no ...
Luan Martin
Patient
I love that they come to your house. They are very professional and I couldn't ask for anything more. I've been taking Myers Cocktails for over 20 years and since moving to this ar...
Melinda Tijerina
Patient
B-12 shot was great boost of energy!
Legitscript certifiedIndividual experiences vary. Testimonials reflect personal opinions and do not guarantee outcomes.
The licensed providers behind your personalized care
Dr. Utkal Patel
MD, Internal Medicine
Critical Care Medicine
Samantha Alonso
Board Certified
Family Nurse Practitioner
Dalila Tarr
FNP-BC
Nurse Practitioner
Dr. Randa Soukieh
Board Certified
Family Medicine
Dr. Rashed Alfarra
Board Certified
Internal Medicine, Nephrology and Critical Care
Carrie Ferguson
FNP, BC
Nurse Practitioner
Christina Case
AGACNP-BC
Nurse Practitioner
Yana Norman
FNP
Nurse Practitioner
Lashanda Roberts
FNP-BC, BSN, RN
Nurse Practitioner
Esther Mwaura
FNP-C, AGACNP-BC
Nurse Practitioner
Dr. Arijit Chowdhury
Board Certified
Internal Medicine
Dr. Sushil Gupta
MD, FCCP
Internal Medicine, Pulmonary & Critical Care
Tynetta Eleazer
MSN, RN, APRN, FNP-BC
Nurse Practitioner
Brandon Olinger
AGACNP-BC
Nurse Practitioner
Brenda Ballard
Integrative Health Practitioner
Health Coaching
Lauren Grube
Integrative Health Practitioner
Health Coaching
Frequently Asked Questions
Get answers to commonly asked questions.
Still have questions? Contact us