Epithalon injectable peptide vial

Epithalon (also spelled epitalon) is a pineal-gland tetrapeptide studied for telomerase activity, sleep, and circadian rhythm, and popular in longevity protocols. Human evidence is early-stage. Ivologist prescribes it in cycles after a medical telehealth consultation. Epithalon is not FDA-approved.

Epithalon

A clinician-guided Epithalon protocol for individuals exploring longevity and sleep support, prescribed in 12-week cycles. Includes provider consultation, medication supply, and care guidance.

Choose your cycles3 × 5 mL vials per cycle
1 cycleLaunch special
$899$800

12 weeks · 1 × 12-week cycle · $800/cycle

You save $99

Every cycle includes
  • Clinician consultation
  • Peptide medication
  • Free shipping
  • May require labs

One-time payment, not a subscription. Up to 3 cycles per year. A cycle is the program length; your provider decides whether treatment is right for you and sets your dose, schedule and duration. We do not offer clinical trials. Individual results may vary.

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Studied for Cellular Aging

Epithalon is researched for its potential influence on telomerase activity, the enzyme that maintains telomeres.

Studied for Sleep & Circadian Rhythm

Modeled on a pineal-gland peptide, it's studied for melatonin and circadian regulation. Human evidence is early-stage.

Clinician-Guided Treatment

Licensed providers determine dosing, frequency, and duration based on medical history and clinical evaluation.

Cyclical, Physiologic Approach

Prescribed in 12-week cycles with breaks between them rather than continuous use.

Integrates With Broader Care Plans

When clinically appropriate, may be coordinated alongside longevity, sleep, or aesthetic programs.

All treatment plans require medical evaluation and approval. Individual results may vary.

Take control of your health in 6 simple, affordable steps

Personalized Intake

1

Tell us about your health, goals, and history through a secure intake questionnaire.

Clinician Review

2

A licensed clinician reviews your information and determines what's right for you.

Diagnostic Lab Testing

3

Baseline lab work checks your health markers before any peptide is prescribed.

Clinical Evaluation

4

A provider reviews your labs with you in a live video visit and confirms your suitability for peptide therapy.

Medication Delivered

5

Your prescribed medication is prepared by a partner pharmacy and shipped to your home.

Ongoing Support

6

Your progress is monitored with follow-ups and adjustments as needed.

How the program works

Built around 12-week cycles

Peptide programs are sold in 12-week cycles (about 3 months). You can buy one cycle or a bundle of up to 3 cycles up front, with a maximum of 3 cycles per year.

Labs and a provider consultation are required.

Every peptide program starts with lab work and a live consultation with a licensed provider before anything is prescribed.

A year on the programUp to 3 cycles · 52 weeks
  1. Lab panel includedCycle 112 weeksOne cycle at a time
  2. Cycle 212 weeksBundle of 2 · save 7.5%
  3. Cycle 312 weeksBundle of 3 · save 12.5%
  • Clinician consultation & follow-up access
  • All peptide medication for the cycle
  • Shipping to your door
  • Injection supplies & dosing guide

Peptide therapy

Not sure which peptide program is right for you?

Talk it through first in a free 15-minute provider consultation. A U.S.-licensed provider will go over your goals and health history, explain how the programs work, and help you decide whether one is right for you before you commit to a cycle. There is no obligation to start treatment.

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Understanding Cellular Aging and Circadian Rhythm

Cellular resilience and sleep rhythms shift with age. Learn how clinician-guided Epithalon therapy may support telomerase activity, sleep quality, and circadian balance.

Understanding Cellular Aging & Circadian Rhythm

Learn about Epithalon, how it works, and how clinician-guided therapy may support your longevity and sleep goals.

The Physiology

Proposed Pineal Peptide Signaling

Pineal peptide → Telomerase + melatonin/circadian signaling

Epithalon is modeled on a substance produced by the pineal gland and is studied for supporting telomerase activity and regulating melatonin and circadian rhythm, alongside antioxidant activity. Human evidence is early-stage.

With age, these systems shift, which may affect sleep and cellular resilience.

Symptoms

Symptoms & Signals

Some individuals report patterns such as:

Poor or non-restorative sleep
Disrupted circadian rhythm
Reduced resilience or slower recovery
General signs of aging
Low energy despite lifestyle effort

Experiencing multiple patterns may warrant clinician evaluation.

Who Is It For?

Who May Benefit from Epithalon?

Epithalon may be considered for adults who are:

Focused on healthy aging and longevity
Prioritizing sleep and circadian support
Seeking a cyclical, conservative approach
Participating in longevity or wellness programs

Clinical evaluation is required. Your eligibility will be determined by a licensed provider.

Epithalon vs Melatonin

Epithalon vs Melatonin

How the two differ. Epithalon's human evidence is early-stage.

Epithalon

A peptide studied for supporting the body's own circadian and telomerase-related pathways.

  • Cyclical dosing
  • Researched for cellular-aging markers
  • Studied for effects upstream of sleep signaling

Melatonin

A hormone taken directly to signal sleep timing.

  • •Direct supplementation
  • •Targets sleep onset
  • •Not used for cellular-aging pathways

Treatment decisions are determined through clinician evaluation.

Protocol

Protocol Philosophy

Epithalon is prescribed in 12-week cycles.

An example, not your plan. This page offers injectable Epithalon only. The 12-week cycle you choose is the program: clinician consultation, peptide medication and free shipping; labs may be required. It is not a dosing schedule; your provider decides your dose, how often and for how long.

Cycle (12 Weeks)

Dosing runs through the cycle on the schedule your clinician sets.

Between Cycles

A break between cycles rather than continuous use.

Repeat (Up to 3 Cycles a Year)

Your clinician reviews your response before another cycle.

Ongoing

Any longer-term use is your provider's decision, reviewed cycle by cycle.

Responses vary by individual.

Research Findings and Limits

Research Findings and Limits

What Epithalon has been studied for, and the kind of study behind each:

Early researchCellular-aging markers
Early researchSleep quality and circadian rhythm
Early researchAntioxidant/cellular resilience
Care planCan sit alongside a longevity program

Limits of the research. Epithalon's human evidence is early-stage and long-term human data is limited. No outcome is guaranteed.

Individual responses vary.

Designed for Safety.Guided by Clinicians.

  • Early-stage evidence — Epithalon is compounded, not FDA-approved, and its human data is limited, which your provider weighs with you
  • Gradual, not instant — sleep-wake and longevity support are assessed over a full 12-week cycle, not in days
  • Generally very well tolerated — mild injection-site reactions are the most commonly reported effect

Epithalon is screened for contraindications (active or recent cancer, pregnancy and breastfeeding) before it is prescribed

Epithalon vial standing on a stone plinth

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Compounded peptides ship from licensed US pharmacies. Certain products and delivery forms may vary by state — our team will help you find the best option for your needs.

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Frequently Asked Questions

Get answers to commonly asked questions.

Epithalon (epitalon) is a synthetic four-amino-acid peptide modeled on a pineal-gland substance. It is studied as a longevity and circadian-regulation peptide and is available as a compounded prescription medication.

It is studied for cellular-aging markers, sleep quality, and circadian rhythm. Human evidence is early-stage, so it is used as a supervised longevity tool rather than a proven treatment.

No. Epithalon is not FDA-approved. It is compounded by licensed 503A pharmacies and prescribed individually after a medical evaluation.

Research suggests epithalon may influence telomerase, the enzyme that maintains telomeres, and help regulate melatonin and circadian signaling, with antioxidant activity. Much of the human data is early-stage.

It is a subcutaneous injection prescribed in 12-week cycles, with up to three cycles a year. Your provider sets the exact dosing schedule within each cycle.

Still have questions? Contact us